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Ligand-target analysis using NicheNet revealed altered intercellular communication pathways, with predicted ligands for upregulated and downregulated cardiomyocyte genes including TGF1 and BDNF ( Figure S4D-G )

Choosing a specific agent involves weighing evidence, dosing preferences, comorbidities, and safety profile

Supplementary Materials The following supporting information can be downloaded at: Table S1: Full database search strings, Table S1B: Data-charting form, Section S1C: Deduplication rules, Section S1D: Controlled exclusion reasons

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